Heat shock protein 60, animation

Videonummer 11938281
Heat shock protein 60 (Hsp60), animation. Hsp60 (purple) is a molecular chaperone and a member of the heat shock protein (HSP) family. HSPs are a group of proteins whose levels increase when cells are exposed to raised temperatures or other stress. Hsp60 is found in the mitochondrial matrix and facilitates the correct folding of proteins (green). If a protein does not fold into the correct three dimensional shape, it cannot function properly. Hsp60 identifies misfolded proteins and takes them into one of its two cavities. These provide a protected environment for the protein to refold. The cavity is capped by a chaperonin 10 protein (red), which allows the cavity to expand. Once the protein is correctly folded hydrolysis of ATP (adenosine triphosphate) releases chaperonin 10 and the protein.
Lizenzart: Lizenzpflichtig
Credit: Science Photo Library / Biocosmos / Francis Leroy & Jana Hermanova
Modell-Rechte: nicht erforderlich
Länge: 40 Sekunden
Seitenverhältnis: 16:9
Restrictions: -

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