Glucose metabolism regulation

Videonummer 11937684
Glucose metabolism regulation. Animation showing how positive regulation by the catabolic activator protein (CAP) affects glucose metabolism. The CAP molecule is needed to activate the genes that metabolise sugars other than glucose. This occurs when the CAP molecule (brown) binds to a region of DNA (deoxyribonucleic acid, multicoloured helix) upstream of ribonucleic acid polymerase (RNA Pol, blue). The RNA Pol enzyme then moves down the DNA strand and transcribes the genes known as the lactose operons (ZYA), triggering metabolism of lactose and other sugars. This process only occurs if a molecule of cyclic adenosine monophosphate (cAMP, white), is itself bound to the CAP molecule. The presence of cAMP inside the cell is in reverse proportion to the glucose concentration. When glucose concentration is weak, cAMP concentration is high and CAP activation occurs. When glucose is abundant, cAMP concentration is low and glucose is metabolised instead (glycolysis, lower left). For this animation without labels, see K004/3396.
Lizenzart: Lizenzpflichtig
Credit: Science Photo Library / Biocosmos / Francis Leroy & Mathilde Vanspeybrouck
Modell-Rechte: nicht erforderlich
Länge: 39 Sekunden
Seitenverhältnis: 16:9
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