Excitatory and inhibitory synapses

Videonummer 11936415
Excitatory and inhibitory synapses. Animation showing how a neurotransmitter can have different effects on a post-synaptic membrane. The sequences show a neurotransmitter (purple) being released by the synaptic bud (blue, upper left) and activating ion channels (yellow) on the post-synaptic membrane (lower left). This is shown in more detail at centre, with the activated ion channel (yellow) opening to allow ions through. The first sequence shows acetylcholine activating sodium ions (Na+, green) and reversing the membrane polarity. This produces an action potential on the graph at far right known as an excitatory post-synaptic potential (EPSP). The second sequence shows the neurotransmitter GABA (gamma-aminobutyric acid) opening an ion channel and inhibiting the occurrence of a new action potential by allowing chloride ions (Cl-, red) to reinforce the original polarity. This is an inhibitory post-synaptic potential (IPSP). Acetylcholine is mainly involved in the neuromuscular synapses, while GABA is the main inhibitor in the brain. For this animation without labels, see K004/0934.
Lizenzart: Lizenzpflichtig
Credit: Science Photo Library / Biocosmos / Francis Leroy & Michael Pierard
Modell-Rechte: nicht erforderlich
Länge: 40 Sekunden
Seitenverhältnis: 16:9
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