Inhibition of bacterial wall growth by penicillin, illustration

Bildnummer 13950923
Inhibition of bacterial wall growth by penicillin, illustration
Illustration showing the antibiotic penicillin (red molecule) inhibiting bacterial cell wall (blue layer) growth. Penicillin was discovered by the Scottish microbiologist Alexander Fleming (1881-1955, top left) from the fungus Penicillium (yellow, right). The bacterial cell wall is made up of peptidoglycan, which forms a rigid mesh-like layer outside the plasma membrane (orange layer). To build the cell wall, peptidoglycan monomers (building blocks) are cross-linked together with the help of an enzyme called transpeptidase. This process is repeated to allow the cell to grow and replicate. Transpeptidase is also referred to as a penicillin-binding protein (PBP). When penicillin or other antibiotics in the beta-lactam family bind to transpeptidase, it inhibits its crosslinking activity, preventing new cell wall formation.
Lizenzart: Lizenzpflichtig
Credit: Science Photo Library / Leroy, Francis / Biocosmos
Bildgröße: 3720 px × 5135 px
Modell-Rechte: nicht erforderlich
Eigentums-Rechte: nicht erforderlich
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