Glioblastoma, light micrograph. Glioblastoma is a high-grade (WHO Grade IV) aggressive astrocytoma primarily seen in adults. Microscopically, it shows hypercellularity, greater nuclear pleomorphism and hyperchromasia, and increased mitotic activity. The presence of necrosis is one of the histologic hallmarks of glioblastoma. Necrotic areas are usually seen in serpentine pattern (shown here) or geographic pattern in hypercellular foci. Tumor cells often aggregate around the periphery of necrotic areas creating pseudopalisading. | |
Lizenzart: | Lizenzpflichtig |
Credit: | Science Photo Library / WEBPATHOLOGY |
Bildgröße: | 4096 px × 3200 px |
Modell-Rechte: | nicht erforderlich |
Eigentums-Rechte: | nicht erforderlich |
Restrictions: | - |