Anaplastic astrocytoma, light micrograph. Infiltrating astrocytomas account for almost 80% of adult primary brain tumours. The usual location is cerebral hemispheres and the most commonly affected age group is 4th to 6th decades. The histologic spectrum ranges from diffuse fibrillary astrocytomas (WHO Grade II), through anaplastic astrocytomas (WHO Grade III) to Glioblastoma (WHO Grade IV). WHO Grade I is reserved for Pilocytic astrocytomas. Anaplastic astrocytomas (WHO Grade III; shown in this image) exhibit greater degree of cellularity, nuclear pleomorphism, and mitotic activity as compared to low-grade astrocytomas. However, necrosis and endothelial proliferation - the two hallmarks of Glioblastoma (WHO Grade IV) - are absent. | |
Lizenzart: | Lizenzpflichtig |
Credit: | Science Photo Library / WEBPATHOLOGY |
Bildgröße: | 4096 px × 3200 px |
Modell-Rechte: | nicht erforderlich |
Eigentums-Rechte: | nicht erforderlich |
Restrictions: | - |