Embryonal rhabdomyosarcoma, light micrograph

Bildnummer 13243833
Embryonal rhabdomyosarcoma, light micrograph
Embryonal rhabdomyosarcoma, light micrograph. Rhabdomyosarcoma (RMS) is a malignant soft tissue tumour that shows skeletal muscle differentiation. There is no evidence it arises from skeletal muscle cells. Many cases occur at sites with scant or no skeletal muscle tissue. RMS can occur anywhere in the body, but affects three regions more commonly - the head and neck, genitourinary tract and retroperitoneum, and upper and lower extremities. The World Health Organization recognizes four major types of rhabdomyosarcomas - embryonal, alveolar, pleomorphic and spindle cell/sclerosing type. The image shows a poorly-differentiated embryonal rhabdomyosarcoma which resembles developing muscle at 5 to 8 weeks gestation. It is composed of primitive-appearing small, round or spindle-shaped cells with hyperchromatic nuclei and scant cytoplasm. Mitotic activity is brisk. Rhabdomyoblasts with abundant eosinophilic cytoplasm are either absent or present in isolated pockets within the tumour.
Lizenzart: Lizenzpflichtig
Credit: Science Photo Library / WEBPATHOLOGY
Bildgröße: 4096 px × 3200 px
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