When a protein is damaged or its function is no longer required, it is tagged for degradation by the addition of several ubiquitin marker proteins. One way multiple ubiquitin markers are added is by a condensation reactions between the C-thermical carboxyl group of the first ubiquitin (right) and a Lys residue of the new ubiquitin (left). The proteins are linked by a covalent isopeptide bond, shown here in ball-and-stick form. | |
Lizenzart: | Lizenzpflichtig |
Credit: | Science Photo Library / Science Source / Greg Williams |
Bildgröße: | 5100 px × 3000 px |
Modell-Rechte: | nicht erforderlich |
Eigentums-Rechte: | nicht erforderlich |
Restrictions: | - |