Carvedilol, 12.5mg. Carvedilol, (Coreg, Dilatrend, Eucardic), (12.5mg pills), is a non-selective beta blocker used in the treatment of mild to moderate congestive heart failure as an adjunct to conventional treatments, (ACE inhibitors and diuretics). Norepinephrine stimulates the nerves that control the muscles of the heart by binding to the beta-1- and beta-2-adrenergic receptors. Carvedilol blocks the binding to those receptors, which both slows the heart rhythm and reduces the force of the heart's pumping. Norepinephrine also binds to the alpha-1-adrenergic receptors on blood vessels, causing them to constrict and raise blood pressure. Carvedilol blocks this binding to the alpha-1-adrenergic receptors too, which also lowers blood pressure. |