This composite of 4 axial T2 weighted MRI images of a newborn shows a normal pattern of myelination. The general progression of myelination in infants is from inferior to superior,central to peripheral and posterior to anterior. Immature myelinated regions of the brain have less fat and more water content therefore on T1 weighted images the immature regions of myelination look darker and brighter on T2 weighted images. A relatively normal adult pattern of myelination is acheived by about 18 months of age. Here the predominant pattern on this T2 weighted image is one of immature myelination with increased signal intensity | |
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Credit: | Science Photo Library / Living Art Enterprises, LLC |
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