Philadelphia chromosome. Coloured light micrograph of two chromosome pairs with a genetic defect that causes chronic myelogenous leukaemia (CML). Pairs of chromosomes comprise a paternal and a maternal chromosome. From left is a normal chromosome 9,a larger defective chromosome 9,a normal chromosome 22 and a smaller defective chromosome 22. This translocational defect resulted from an exchange of material between the two defective chromosomes. The four chromosomes have replicated and will pass the defect to a new cell. The defective chromosome 22,when present in a bone marrow stem cell,leads to the increased white blood cell count in CML | |
Lizenzart: | Lizenzpflichtig |
Credit: | Science Photo Library / Addenbrookes Hospital / Dept. of Clinical Cytogenetics |
Bildgröße: | 1750 px × 1250 px |
Modell-Rechte: | nicht erforderlich |
Eigentums-Rechte: | nicht erforderlich |
Restrictions: | - |