SV40 antigen and tumour suppressor. Molecular model of the simian virus (SV40) large T antigen bound to a retinoblastoma tumour suppressor (Rb). Large T antigens play a role in regulating the viral life cycle of the polyomaviridae viruses,such as SV40. SV40 is potentially tumour-causing in primates and humans. Rb proteins encourage normal cell cycles,thus preventing the formation of tumours. When the large T antigen binds to Rb,the tumour suppressor's action is blocked,and the development of malignant tumours becomes more likely | |
Lizenzart: | Lizenzfrei |
Credit: | Science Photo Library / Laguna Design |
Modell-Rechte: | nicht erforderlich |
Eigentums-Rechte: | nicht erforderlich |
Restrictions: | - |