Stomach ulcer. Light micrograph of a gastric (stomach) ulcer. The uppermost layer of epithelial cells lining the stomach,called the mucosa (light pink),has been degraded by excessive stomach acid secretion,forming an ulcer base. This acid,often combined with excess alcohol and caffeine,attacks the stomach wall,causing pain and discomfort. If the wall's protective mucus has become thinner,due to stress or infection,the acid can eventually perforate it and leak into the abdominal cavity. Treatment of mild ulcers is with antacid drugs,but severe cases require surgical removal of part or all of the stomach (gastrectomy) |