Sirtuin enzyme and p53. Computer artwork of a sirtuin (Sir2) enzyme (pink) bound to a p53 peptide (orange). Sir2 enzymes form a unique class of NAD(+)-dependent deacetylases that are required for diverse biological processes,including transcriptional silencing,regulation of apoptosis (programmed cell death),fat mobilisation,and lifespan regulation. NAD is shown as a stick model (centre). p53 is crucial in multicellular organisms,where it regulates the cell cycle (the means by which cells replicate) and prevents the proliferation of cells with damaged DNA | |
Lizenzart: | Lizenzpflichtig |
Credit: | Science Photo Library / Andrade, Ramon / 3dciencia |
Bildgröße: | 3623 px × 4830 px |
Modell-Rechte: | nicht erforderlich |
Eigentums-Rechte: | nicht erforderlich |
Restrictions: | - |