Human SARM1 complexed with inhibitor dHNN, molecular model. SARM1 (sterile alpha and TIR motif containing 1) is an enzyme that is the most evolutionarily conserved member of the Toll-Interleukin receptor (TIR) family. SARM1 regulates axonal degeneration through its NAD-metabolizing activity and is a drug target for neurodegenerative disorders. It is shown in green and violet, the inhibitor dHNN (dehydronitrosonisodipine) in orange. | |
Lizenzart: | Lizenzpflichtig |
Credit: | Science Photo Library / Laguna Design |
Bildgröße: | 4150 px × 4150 px |
Modell-Rechte: | nicht erforderlich |
Eigentums-Rechte: | nicht erforderlich |
Restrictions: | - |