Nodular lymphocyte-predominant Hodgkin lymphoma, micrograph

Bildnummer 13387822
Nodular lymphocyte-predominant Hodgkin lymphoma, micrograph
Light micrograph of nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL). NLPHL is a rare, germinal centre-derived, B-cell lymphoma that is biologically distinct from classic Hodgkin lymphoma (cHL). The two entities differ in their clinical presentation, epidemiology, morphology, immunophenotype, and molecular genetics. Nodular and B-cell rich patterns of NLPHL are more common and considered typical. They present with localized disease and generally pursue an indolent course. Less frequently, the involved lymph nodes show more diffuse or T-cell rich infiltrates (variant patterns). These patients frequently have advanced disease with splenic, liver, or bone marrow involvement, B-symptoms, and a more aggressive clinical course.
Lizenzart: Lizenzpflichtig
Credit: Science Photo Library / WEBPATHOLOGY
Bildgröße: 4096 px × 3000 px
Modell-Rechte: nicht erforderlich
Eigentums-Rechte: nicht erforderlich
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