Craniopharyngioma, light micrograph

Bildnummer 13296452
Craniopharyngioma, light micrograph
Craniopharyngioma, light micrograph. Craniopharyngioma is a WHO Grade 1 epithelial tumour usually seen in the sellar/suprasellar region. It arises most likely from the remnants of Rathke's pouch. Some cases may have their origin in misplaced odontogenic rests along pituitary stalk. Grossly, they are often solid and cystic with areas of calcification. Craniopharyngiomas are subdivided into two types based on morphologic features: 1) Adamantinomatous (90% of cases) seen mostly in children and 2) Papillary (10% of cases) seen mostly in adults. Papillary craniopharyngiomas more often tend to be solid and rarely show calcification (unlike adamantinomatous variant). They are composed of sheets of well-differentiated non-keratinizing squamous epithelium (WHO Grade 1). Dehiscence of epithelium around fibrovascular cores often results in pseudopapillary architecture as seen here.
Lizenzart: Lizenzpflichtig
Credit: Science Photo Library / WEBPATHOLOGY
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