Small lymphocytic lymphoma, light micrograph. B-cell chronic lymphocytic leukemia and small lymphocytic lymphoma are the most common mature B-cell neoplasms and are considered to be different manifestations of the same disease. Chronic lymphocytic leukemia affects middle-aged and elderly patients. The mature-appearing neoplastic B-cells are predominantly in blood and bone marrow. In small lymphocytic lymphoma, the neoplastic cells are mainly extramedullary with very few leukemic cells in blood. This image shows small lymphocytic lymphoma involving the spleen. It is composed of a uniform population of small to medium-sized B lymphocytes. They have slightly irregular nuclear contours, condensed chromatin, and inconspicuous nucleoli. Mitotic activity is not increased. | |
Lizenzart: | Lizenzpflichtig |
Credit: | Science Photo Library / WEBPATHOLOGY |
Bildgröße: | 4730 px × 3695 px |
Modell-Rechte: | nicht erforderlich |
Eigentums-Rechte: | nicht erforderlich |
Restrictions: | - |