Tyrosine kinase and bosutinib complex. Computer illustration showing a molecule of bosutinib (spheres) bound to a tyrosine kinase molecule (ribbons). Tyrosine kinase is an enzyme that can transfer a phosphate group from ATP (adenosine triphosphate) to a protein in a cell. Bosutinib is a Bcr-Abl tyrosine-kinase inhibitor (TKI),a group of TKIs that inhibit tyrosine kinase associated with the Philadelphia chromosome (Bcr-Abl). Bcr-Abl TKIs are the first-line therapy for most patients with chronic myelogenous leukaemia (CML). Over 90 percent of CML cases are caused by a chromosomal abnormality that results in the formation of a so-called Philadelphia chromosome | |
Lizenzart: | Lizenzpflichtig |
Credit: | Science Photo Library / Andrade, Ramon / 3dciencia |
Bildgröße: | 3508 px × 4960 px |
Modell-Rechte: | nicht erforderlich |
Eigentums-Rechte: | nicht erforderlich |
Restrictions: | - |